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李鸣

发布时间:2013-03-25 来源:本站原创 作者:本站编辑   浏览次数:

个人简介

李鸣,男,1968年生,教授,博士生导师,美国内布拉斯加林肯大学终身教授,西南大学心理学部客座教授,教育部“长江学者” 讲座教授。

2002年获加拿大多伦多大学心理学专业博士学位。2002年至2005年,在加拿大成瘾和精神健康研究中心从事博士后研究,2005年至今在美国内布拉斯加林肯大学任教。2015年获得被评为内布拉斯加大学文理学院杰出创新贡献奖。2016年入选教育部“长江学者”奖励计划,被授予“长江学者”讲座教授称号。此外,李鸣博士还是国内外多项科研基金基金评审人、多个神经科学和心理学领域著名专业杂志的审稿人。

博士在精神疾病心理理学研究域进行了大量卓有成效的研究,在国际专业期刊先后发表研究论文71 篇,尤其在抗精神药物的心理药理学机制和母性行为的5-羟色胺调控机制研究方面卓有建树。先后主持了多项美国联邦政府资助的重大研究项目,其中包括抗精神病的行为学机制、关于5-羟色胺参与母性行为和产后抑郁的机制。他在精神疾病和母性行为动物学研究方面取得了具有影响力的丰硕成果。先后发表SCI收录科研论文70余篇,总引用次数多达1400余次。因其在该领域的杰出贡献,李鸣博士多次受邀参加国内国际学术会议并做大会报告。 

联系方式

E-mail:            mli@unl.edu
美国单位链接: http://psychology.unl.edu/ming-li
谷歌学术Google Scholar链接 http://scholar.google.com/citations?user=jxpWKGAAAAAJ&hl=en

 

研究领域

精神疾病的心理理学研究域,现主要从事精神分裂症、抗精神病药物的长期作用机制研究、母性行为的心理药理学机制及神经生物学机制领域的研究。比如:抗精神病药物对大脑及心理功能的影响;精神类疾病的动物模型;药物成瘾与精神分裂症的心理药理学机制,以及啮齿类动物母性行为的神经生物学机制。

教育经历

1996-2002,加拿大多伦多大学,博士,导师:Alison S. Fleming

1993-1996,北京大学心理学系,硕士,导师:肖健

1987-1991,北京大学心理学系,学士

 

研究工作经历

2011-今,美国内布拉斯加林肯大学,副教授,教授

2005-2011,美国内布拉斯加林肯大学,助理教授

2002-2005,加拿大成瘾与精神健康研究中心,博士后

主要荣誉

2015            College of Arts and Sciences Outstanding Research and Creative Activity Award

2014            Fellow, Midwestern Psychological Association

2013            Fellow, American Psychological Association Div. 6.

20062007    Recipient of the UNL Parents Association “Certificate of  Recognition for Contributions to Students”

2004                D. G. Marquis Behavioral Neuroscience Award for the best paper published in Behavioral Neuroscience.

20022005    Ontario Mental Health Foundation Postdoctoral Fellowship

主持项目

1. Ming Li (PI). NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT, R03HD079870, “Adolescence neurogenesis mechanisms of antipsychotic sensitization and tolerance”, 02/01/2015-01/31/2017, $157,802, 在研主持

2. Ming Li (PI). DHHS-Nat Inst Mental Health, R01MH097718, “Serotonin, Maternal Behavior and Postpartum Depression”, 06/01/2013-03/31/2018, $1,497,476在研主持

3. Ming Li (PI). DHHS-Nat Inst Mental Health, R01MH085635, “Behavioral mechanisms of antipsychotic action”03/22/2010-01/31/2015, $1,447,532在研主持

4. Ming Li (Co-Investigator). Department of Defense (DoD) FY12 Autism Research Program, AR120096, “Mechanisms of Synaptic Alterations in a Neuroinflammation Model of Autism”, 09/30/2013-09/29/2016, $579,822.00在研主持

5. Ming Li (PI). Nebraska Health and Human Services, “Iptakalim for nicotine use in schizophrenia: A preclinical test”, 07/01/2010-06/30/2011, $40,000已结题主持

6. Ming Li (PI). DHHS-Nat Inst Mental Health, R21 MH079894, “Anxiolytic Property of Atypical Antipsychotics”, 01/01/2008-12/31/2010, $362,145已结题主持

7. Ming Li (PI). DHHS-Nat Inst Mental Health, R03 MH080822, “Antipsychotic Drugs and Maternal Behavior: A Preclinical Investigation”, 09/15/2007-07/31/2010, $132,750已结题主持

8. Ming Li (PI). Stanley Medical Research Institute, “Iptakalim: A Potential Antipsychotic Drug with Novel Mechanisms”, 08/2007-07/2010, $150,000已结题主持

9. Ming Li (PI). National Alliance for Research on Schizophrenia and Depression (NARSAD), Young Investigator Award, “Behavioral Mechanisms of Action of Atypical Antipsychotics: A Preclinical Investigation”, 07/2007-06/2010, $60,000已结题主持

10. Ming Li (PI). Nebraska Health and Human Services, 2008-03B, “Nicotine Effects in Adolescent and Adult Rats”, 07/01/2008-06/30/2009, $40,000已结题主持

11. Ming Li (PI). UNL Layman New Direction award, Central Receptor Mechanisms of Antipsychotic Drugs: A Central Infusion StudyJune 2012-May 2013, $16,108. 已结题主持

12. Ming Li (Co-Investigator, PI: Anna Dunaevsky). NU Nebraska Research Initiative Grant, “Nanotherapeutics in Neuroinflammation Model of Autism”, 7/1/12- 6/30/13, $100,000已结题参与

13. Ming Li (Co-Investigator). UNL Life Sciences Competitive, “Gene Therapy Against Neurodegenerative Disorders Associated with Pesticide Exposure”, 07/2011-06/2013, $72,000已结题参与

14. Ming Li (PI). Faculty seed grant, “Characterizing Reconsolidation of Persistent Avoidance Responding”, 2008-2009, $9,943已结题主持

15. Ming Li (PI). Faculty seed grant, “How Antipsychotic Drugs Work Psychologically?------An Animal Behavioral Investigation”, 2006-2007, $9,980已结题主持

16. Ming Li (PI) (co-I: Dr. Bevins). UNL Layman award, “Persistent Avoidance Responding as an Animal Model of Schizophrenia”, 2006/06- 2007/05, $9,995已结题主持

发表论文 ( * 通讯作者)

Peer reviewed:

1.         Liu, P, Zhang, J, Li, M, & Sui, N (2016). Distinctive Roles of 5-aza-2′-deoxycytidine in Anterior Agranular Insular and Basolateral Amygdala in Reconsolidation of Aversive Memory Associated with Morphine in Rats. Frontiers in Behavioral Neuroscience, 10. doi: 10.3389/fnbeh.2016.00050

2.         Li, M* and Chou, SY (2016): Modeling postpartum depression in rats: Theoretic and methodological issues, Zoological Research  37(2): 1-11, 2016

3.         Gao, J, Feng, M, Swalve, N, Davis, C, Sui, N and Li, M* (2016): Effects of repeated quetiapine treatment on conditioned avoidance responding in rats; European Journal of Pharmacology.

4.         Coiro P, Padmashri R, Suresh A, Spartz E, Pendyala G, Chou S, Jung Y, Meays B, Roy S, Gautam N, Alnouti Y, Li M, Dunaevsky A (2015) Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders. Brain Behav Immun.

5.         Yang Y, Qin J, Chen W, Sui N, Chen H, Li M* (2015). Behavioral and pharmacological investigation of anxiety and maternal responsiveness of postpartum female rats in a pup elevated plus maze, Behavioural Brain Research, 2015 Jul 6;292:414-427. doi: 10.1016/j.bbr.2015.07.010.

6.         Li, M* (2015): Antipsychotic Drugs on Maternal Behavior in Rats, Behavioural Pharmacology, 2015 Sep;26(6):616-26. doi: 10.1097/FBP.0000000000000168.

7.         Swalve, N, Barrett, S, Bevins, RA and Li, M (2015): Examining the Reinforcement-Enhancement Effects of Phencyclidine and Its Interactions with Nicotine on Lever-Pressing for a Visual Stimulus, Behavioural Brain Research, Sep 15;291:253-9. doi: 10.1016/j.bbr.2015.05.043.

8.         Chou, SY, Jones, S and Li M* (2015): Adolescent olanzapine sensitization is correlated with hippocampal stem cell proliferation in a maternal immune activation rat model of schizophrenia, Brain Research, Aug 27;1618:122-35. doi: 10.1016/j.brainres.2015.05.036.

9.         Swalve, N, Pittenger, S, Bevins, RA and Li, M (2015): Behavioral Effects of Phencyclidine on Nicotine Self-Administration and Reinstatement in the Presence or Absence of a Visual Stimulus in Rats, Psychopharmacology, Aug;232(16):2877-87. doi: 10.1007/s00213-015-3923-0.

10.       Gao J, Li M* (2015): Repeated administration of aripiprazole produces a sensitization effect in the suppression of avoidance responding and phencyclidine-induced hyperlocomotion and increases D2 receptor-mediated behavioral function, Journal of Psychopharmacology, Apr;29(4):390-400

11.       Chou, SY; Davis, C; Jones, S and Li, M* (2014): Repeated effects of the neurotensin receptor agonist PD149163 in three animal tests of antipsychotic activity: assessing for tolerance and cross-tolerance to clozapine, Pharmacology, Biochemistry and Behavior, 2014 Nov 26;128C:78-88. doi: 10.1016/j.pbb.2014.11.015.

12.       Feng, M, Gao, J, Sui, N and Li, M* (2015): Effects of central activation of serotonin 5-HT2A/2C or dopamine D2/3 receptors on the acute and repeated effects of clozapine in the conditioned avoidance response test; Psychopharmacology, 2015 Apr;232(7):1219-30

13.       Shu, Q, Qin, RY, Chen, YZ, Hu, G* and Li, M* (2014): Asenapine sensitization from adolescence to adulthood and its potential molecular basis, Behavioural Brain Research, 2014 Oct 15;273:166-76. doi: 10.1016/j.bbr.2014.07.042. Epub 2014 Aug 2.

14.       Gao J, Li M* (2014): Differential Effects of Intermittent versus Continuous Haloperidol Treatment throughout Adolescence on Haloperidol Sensitization and Social Behavior in Adulthood, Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2014 Oct 3;54:67-75.

15.       Sun, T, Liu, XF, and Li, M* (2014): Environmental Cues on Behavioral Efficacy of Haloperidol, Olanzapine and Clozapine in Rats, Behavioural Pharmacology, 2014 Aug;25(4):277-86. doi: 10.1097/FBP.0000000000000047

16.       Chen, WH, Zhang, Q, Su, WX, Zhang, HR, Yang, Y, Qiao, J, Sui, N, and Li, M* (2014): Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats, Pharmacology, Biochemistry and Behavior, 117: 25-33.

17.       Navarro-Yepes J, Zavala-Flores L, Anandhan A, Wang F, Skotak M, Chandra N, Li M, Pappa A, Martinez-Fong D, Del Razo LM, Quintanilla-Vega B, Franco R (2014) Antioxidant gene therapy against neuronal cell death. Pharmacol Ther 142: 206-30.

18.       Qiao, J, Gao J, Shu, Q, Zhang, QL, Hu, G, and Li, M* (2014), Long-lasting sensitization induced by repeated risperidone treatment in adolescent Sprague-Dawley rats: A possible D2 receptor mediated phenomenon? Psychopharmacology, 231: 1649-59. PMID: 24363078.

19.       Shu, Q, Hu, G and Li, M* (2013): Adult Response to Olanzapine or Clozapine Treatment is altered by Adolescent Antipsychotic Exposure: A Preclinical Test in the Phencyclidine Hyperlocomotion Model, Journal of Psychopharmacology.

20.       Li, M* and He, W (2013): An automatic recording system for the study of escape from fear in rats, Behavioral Processes, 100, 13–17.

21.       Gao J, Li M* (2013) Time-dependence of risperidone and asenapine sensitization and associated D receptor mechanism. Behav Brain Res, 257: 286-94.

22.       Qiao, J, Zhang, QL, Li M* (2013) Long-term impacts of adolescent risperidone treatment on behavioral responsiveness to olanzapine and clozapine in adulthood, Progress in Neuropsychopharmacology & Biological Psychiatry, 177-85.

23.       S. Charntikov, N. Swalve, S. Pittenger, K. Fink, S. Schepers, G. C. Hadlock, A. E. Fleckenstein, G. Hu, M. Li, & R. A. Bevins (2012): Iptakalim attenuates self-administration and acquired goal-tracking behavior controlled by nicotine, Neuropharmacology, 37: 876-84.

24.       Qin, Chen and Li, M* (2013): Repeated Asenapine Treatment Produces a Sensitization Effect in Two Preclinical Tests of Antipsychotic Activity, Neuropharmacology, Aug 14;75C:356-364. doi: 10.1016/j.neuropharm.2013.05.031

25.       Shu, Q, Hu, G and Li, M* (2013): Is Brain-derived Neurotrophic Factor a Possible Mechanism Underlying Risperidone Sensitization in Adolescent Rats? Biochem & Pharmacol S1: 004. doi:10.4172/2167-0501.S1-004, [Open Access]

26.       Qiao J, Li H, Li, M* (2013) Olanzapine sensitization and clozapine tolerance: from adolescence to adulthood in the conditioned avoidance response model. Neuropsychopharmacology 38: 513-24.

27.       Feng, M, Sui, N and Li, M* (2012): Environmental and behavioral controls of the expression of clozapine tolerance: Evidence from a novel across-model transfer paradigm, Behavioural brain research, 2012 Oct 23. doi:pii: S0166-4328(12)00648-1. 10.1016/j.bbr.2012.10.009.

28.       Feng, M, Sui, N and Li, M* (2012): Avoidance disruptive effect of clozapine and olanzapine is potentiated by increasing the test trials: Further test of the motivational salience, Pharmacology, Biochemistry and Behavior, 103: 467-473.

29.       Zhao, CJ and Li, M* (2012): Neuroanatomical substrates of the disruptive effect of olanzapine on rat maternal behavior as revealed by c-Fos immunoreactivity, Pharmacology, Biochemistry and Behavior, 2012 Aug 31;103(2):174-180.

30.       Sparkam, N and Li, M* (2012): Drug-drug conditioning between citalopram and haloperidol or olanzapine in a conditioned avoidance response model: Implications for polypharmacy in schizophrenia, Behavioural Pharmacology, 2012 Oct;23(7):658-68.

31.       Volf, N, Hu, G and Li, M* (2012): Iptakalim preferentially decreases nicotine-induced hyperlocomotion in phencyclidine-sensitized rats: A potential dual action against nicotine addiction and psychosis, Clinical Psychopharmacology and Neuroscience, Dec;10(3):168-79.

32.       Swalve and Li, M* (2012): Parametric studies of antipsychotic-induced sensitization in the conditioned avoidance response model: Roles of number of drug exposure, drug dose, and test-retest interval, Behavioural Pharmacology, 2012 Aug;23(4):380-91

33.       Li, M*, He, W, and Munro, R (2012): Differential effects of acute amphetamine and phencyclidine treatment and withdrawal from repeated amphetamine or phencyclidine treatment on social interaction and social memory in rats, PsyCh Journal, June 2012, 1(1), 56-68.

34.       Zhao, CJ, Sun, T and Li, M* (2012): Neural basis of the potentiated inhibition of repeated haloperidol and clozapine treatment on the phencyclidine-induced hyperlocomotion, Progress in Neuropsychopharmacology & Biological Psychiatry, 2012 Aug 7;38(2):175-82.

35.       Zhang, C and Li, M* (2012): Contextual and behavioral control of antipsychotic sensitization induced by haloperidol and olanzapine, Behavioural Pharmacology, Feb;23(1):66-79.

36.       Li, M*, Sun, T, and Mead, A (2012): Clozapine, but not olanzapine disrupts conditioned avoidance response in rats by antagonizing 5-HT2A/2C receptors, Journal of Neural Transmission, 2012 Apr;119(4):497-505. Epub 2011 Oct 11.

37.       Charntikov, S, Tracy, M, Zhao, CJ, Li, M, Bevins, R (2011): Conditioned response evoked by nicotine conditioned stimulus preferentially induces c-Fos expression in medial regions of caudate-putamen, Neuropsychopharmacology, 2011 Nov 2. doi: 10.1038/npp.2011.263.

38.       Grant, K, LeVan, T, Wells, S, Li, M, Stoltenberg, S, Gendelman, H, Carlo, G and Bevins, R (2012): Methamphetamine-associated psychosis, J Neuroimmune Pharmacol 7: 113-39.

39.       Li, M*, He, W, and Chen, J (2011): Time course of prepulse inhibition disruption induced by dopamine agonists and NMDA antagonists: Effects of drug administration regimen, Pharmacology, Biochemistry and Behavior, 99(3), 509-518.

40.       Li, M*, He, W, and Heupel, K (2011): Administration of clozapine to a mother rat potentiates pup ultrasonic vocalization in response to separation and re-separation: Contrast with haloperidol, Behav Brain Res 222: 385-9.

41.       Li, M*, He, W, and Volf, N (2011): Time course of the attenuation effect of repeated antipsychotic treatment on prepulse inhibition disruption induced by repeated phencyclidine treatment, Pharmacology, Biochemistry and Behavior, 2011 Mar 21;98(4):559-569.

42.       Kathryn Wilson, David Hansen and Ming Li (2011): The Traumatic Stress Response in Child Maltreatment and Resultant Neuropsychological Effects, Aggression and Violent Behavior, 16 (2011) 87–97.

43.       Zhang, C, Fang, YR, and Li, M* (2011): Behavioral mechanisms of the disruptive effect of olanzapine and risperidone in the rat conditioned avoidance response model: further evidence, Pharmacology, Biochemistry and Behavior, 2011 Mar;98(1):155-60. Epub 2010 Dec 29.

44.       Chen, J, Wang, ZC, and Li, M* (2011): Multiple “hits” during postnatal and early adulthood periods disrupt the normal development of sensorimotor gating ability in rats. Journal of Psychopharmacology, 2011;25:379-92.

45.       Li, M*, Sun, T, Zhang, C, Hu, G (2010): Distinct neural mechanisms underlying acute and repeated administration of antipsychotic drugs in rat avoidance conditioning, Psychopharmacology, Sep;212(1):45-57. 

46.       Sun, T, He, W, Hu, G, Li, M* (2010): Anxiolytic property of risperidone and olanzapine as examined in multiple measures of fear in rats. Pharmacology, Biochemistry and Behavior, 2010 May;95(3):298-307.

47.       Sun, T, Zhao, CJ, Hu, G, Li, M* (2010): Iptakalim: A potential antipsychotic drug with novel mechanisms? European Journal of Pharmacology, 2010 May 25;634(1-3):68-76.

48.       Zhao, CJ, Li, M* (2010): C-FOS identification of neuroanatomical sites associated with haloperidol and clozapine disruption of maternal behavior in the rat. Neuroscience, 2010 Apr 14;166(4):1043-55.

49.       Zhao, CJ, Li, M* (2009): The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: A double dissociation between dopamine D2 and 5-HT2A/2C receptors. Pharmacology, Biochemistry and Behavior, 2009 Oct;93(4):433-42. Epub 2009 Jun 17.

50.       Li, M*, He, W, Mead, A (2009) An investigation of the behavioral mechanisms of antipsychotic action using a drug-drug conditioning paradigm. Behavioural Pharmacology, 2009 Mar;20(2):184-94.

51.       Mead A, Li M* (2010) Avoidance-Suppressing Effect of Antipsychotic Drugs is Progressively Potentiated after Repeated Administration: an Interoceptive Drug State Mechanism. Journal of Psychopharmacology, 2010 Jul;24(7):1045-53. Epub 2009 Mar 27.

 

52.       Li, M*, He, W, Mead, A (2009) Olanzapine and risperidone disrupt conditioned avoidance responding in phencyclidine or amphetamine pretreated rats by selectively weakening motivational salience of conditioned stimulus. Behavioural Pharmacology, 20: 84-98.

53.       Sun, T, Hu, G, Li, M* (2009): Repeated antipsychotic treatment progressively potentiates inhibition on phencyclidine-induced hyperlocomotion, but attenuates inhibition on amphetamine-induced hyperlocomotion: Relevance to animal models of antipsychotic drugs. European Journal of Pharmacology, 602:334-342.

54.       Zhao, CJ, Li, M* (2009): Sedation and disruption of maternal motivation underlie the disruptive effects of antipsychotic treatment on rat maternal behavior. Pharmacology, Biochemistry and Behavior, 92: 147-156.

55.       Mead, A, Li, M*, Kapur, S (2008): Clozapine and Olanzapine Exhibit an Intrinsic Anxiolytic Property in Two Conditioned Fear Paradigms: Contrast with Haloperidol and Chlordiazepoxide. Pharmacology, Biochemistry and Behavior, 90 (2008) 551–562

56.       Li, M*, He, W and Munro, R (2008): Amphetamine Selectively Enhances Avoidance Responding to a Less Salient Stimulus in Rats. Journal of Neural Transmission, 2008 May;115(5):773-6.

57.       Parada, M, King, S, Li, M and Fleming, A (2008): The roles of accumbal dopamine D1 and D2 receptors in maternal memory in rats. Behavioral Neuroscience, Apr;122(2):368-76.

58.       Li, M, Fletcher PJ, Kapur S (2007) Time Course of the Antipsychotic Effect and the Underlying Behavioral Mechanisms. Neuropsychopharmacology, 2007, Feb;32(2):263-72.

59.       Smith AJ, Li M, Becker S, Kapur S (2007) Linking Animal Models of Psychosis to Computational Models of Dopamine Function. Neuropsychopharmacology, 2007 Jan;32(1):54-66

60.       Smith A, Li, M, Becker S, Kapur S (2006) Dopamine, prediction error and associative learning: A model-based account. Network 17:61-84.

61.       Li, M, Budin, R, Fleming, A, and Kapur, S (2005) Effects of novel antipsychotics, amisulpiride and aripiprazole, on maternal behavior in rats. Psychopharmacology (Berl). 2005, 181(3) 600-10.

62.       Li, M., Budin, R, Fleming, A, and Kapur, S (2005) Effects of chronic typical and atypical antipsychotic drug treatment on maternal behavior in rats. Schizophrenia Research, 75/2-3 pp 325-336.

63.       Li, M. Parkes, J, Fletcher, PJ, and Kapur, S. (2004) Evaluation of the motor initiation hypothesis of APD-induced conditioned avoidance decreases. Pharmacology, Biochemistry and Behavior, 78(4), 811-819.

64.       Smith, A, Li, M, Becker, S and Kapur, S. (2004) A Model of Antipsychotic Action in Conditioned Avoidance: A Computational Approach. Neuropsychopharmacology, 2004 Jun, 29(6) 1040-9.

65.       Li, M., Davidson, P, Budin, R, Kapur, S and Fleming, A (2004) Effects of typical and atypical antipsychotic drugs on maternal behavior in postpartum female rats. Schizophrenia Research, 2004 Sep 1;70(1):69-80.

66.       Li, M. and A.S. Fleming (2003) The nucleus accumbens shell is critical for normal expression of pup-retrieval in postpartum female rats. Behavioural Brain Research, 2003. 145(1-2): p. 99-111.

67.       Li, M. and A.S. Fleming (2003) Differential involvement of nucleus accumbens shell and core subregions in maternal memory in postpartum female rats. Behavioral Neuroscience, 2003. 117(3): p. 426-45.

68.       Lee, A., Li, M. Watchus, J, Fleming AS (1999) Neuroanatomical basis of maternal memory in postpartum rats: selective role for the nucleus accumbens. Behavioral Neuroscience, 1999. 113(3): p. 523-38.

Invited papers

69.       Li, M*, Mead, A, Bevins, RA (2009) Individual Differences in Responding to Nicotine: Tracking Changes from Adolescence to Adulthood. Acta Pharmacol Sin 2009, Jun; 30 (6): 868–878

70.       Kapur, S, Agid, O, Mizrahi, R, and Li, M (2006) How antipsychotics work—From receptors to reality. NeuroRx, 3 (1), 10-21.

71.       Kapur, S, Mizrahi, R, and Li, M (2005) From dopamine to salience to psychosis - Linking biology, pharmacology and phenomenology of psychosis. Schizophrenia Research, 2005 Nov 1;79(1):59-68.

Publications in Chinese

72.       Gao, J and Li, M* (2015): Antipsychotic-induced behavioral sensitization and tolerance and the related neurobiological mechanisms, Translational Medicine Research (Electronic Edition), 2014, 4 (4): 45-53 DOI: 10.3868/j.issn.2095-154x.2015.01.006

73.       Shu, Q, Duan, ZG, Hu, G and Li, M* (2012): Psychological mechanisms of dopamine in psychotic symptoms of schizophrenia: Recent theoretical and empirical advances, CHINESE SCIENCE BULLETIN.

 

Book chapters

74.       Fleming, A, and Li, M (2002). Psychobiology of maternal behavior in non-human mammals. Handbook of Parenting (second edition, eds. Marc H. Bornstein), Mahwah, N.J.: Lawrence Erlbaum Associates, 2002.

Conference presentations

1.         Wu, R, Davis, C, Li, M: Behavioral mechanisms underlying the maternal disruption induced by 5-HT2C agonism, Society for Neuroscience, October 17-21, 2015, Chicago.

2.         Chou, S, Davis, C, Li, M: The effects of prenatal immune activation and infantile repeated maternal separation stress on maternal behavior, Society for Neuroscience, November 15-19, 2014, Washington DC.

3.         Zhang, M, Li, M: Distal exposure to pups reduces startle response without altering prepulse inhibition in postpartum rats, Society for Neuroscience, November 15-19, 2014, Washington DC.

4.         Gao, J, Li, M: The roles of 5-Hydroxytryptamine 2A and 2C receptors in maternal behaviors in rats, Society for Neuroscience, November 15-19, 2014, Washington DC.

5.         Chou, S, Davis, C, Jones, S, Li, M: Assessment of repeated neurotensin receptor activation using three preclinical models of antipsychotic activation, Society for Neuroscience, November 9-13, 2013, San Diego, CA

6.         Swalve, N, Pittenger, S, Bevins, RA and Li, M: The effects of phencyclidine on self-administration of nicotine: A novel hypothesis for the comorbidity of schizophrenia and nicotine abuse. Society for Neuroscience, November 9-13, San Diego, CA

7.         Li, M, Feng, M and Sui, N: Drug--Drug Conditioning Between Nicotine and Clozapine in a Conditioned Avoidance Response Model, American Psychological Association Convention, Honolulu, Hawaii, July 31-August 2, 2013

8.         Chou, SY, Shu, Q, and Li, M: Sensitization and Tolerance to Antipsychotics in Rats Using the Maternal Immune Activation Model, American Psychological Association Convention, Honolulu, Hawaii, July 31-August 2, 2013

9.         Swalve, N, Petracca, M and Li, M: Phencyclidine and Nicotine's Effects on Ultrasonic Vocalizations Induced by a Visual Stimulus, American Psychological Association Convention, Honolulu, Hawaii, July 31-August 2, 2013

10.       Shu, Q, Chou, S, Li, M: Acute Antipsychotic Treatments Alter BDNF Levels in the Adolescent Rat PCP Model, Society of Biological Psychiatry, 68th Annual Scientific Convention, May 16-18, 2013, San Francisco, California.

11.       Li, M: Contextual and Behavioral Control of Antipsychotic-Induced Sensitization and Tolerance, Winter Conference on Animal Learning, and Behavior, Winter Park, Colorado, February 2 - February 6, 2013.

12.       Li, M: Neurobiological mechanisms of antipsychotic sensitization and tolerance: Some preliminary findings, Winter Conference on Animal Learning, and Behavior, Winter Park, Colorado, February 2 - February 6, 2013.

13.       Feng, M, Nan, Su and Li, M: Number of Testing Trials Affects the Avoidance Disruptive Effect of Clozapine and Olanzapine, American Psychological Association Annual Convention, August 2-5, 2012, Orlando, FL.

14.       Zhao, CJ and Li, M: The neural basis underlying the disruptive effect of olanzapine on rat maternal behavior, Society for Behavioral Neuroendocrinology, June 15-18, 2012, Madison, WI.

15.       Li, M, Feng, M and Sui, N: Asymmetrical across-model transfer of clozapine-induced tolerance between the conditioned avoidance response model and phencyclidine hyperlocomotion model, Society for Neuroscience, November 12-16, 2011, Washington DC.

16.       Li, M and Sparkman, N: Classical conditioning in polypharmacy: Drug-drug conditioning of citalopram and haloperidol or olanzapine, November 12-16, 2011, Washington DC.

17.       Li, M and He, W: Time course of the attenuation effect of repeated antipsychotic treatment on prepulse inhibition disruption induced by repeated phencyclidine treatment, Society of Biological Psychiatry, May 11-14, 2011, San Francisco.

18.       Zhang, C, Fang, YR, and Li M: Sensitization Induced by Haloperidol and Olanzapine is Context-Dependent, Midwestern Psychological Association Conference, May 5-7, 2011, Chicago.

19.       Swalve, N and Li, M: Characterization of the sensitization-like effect of antipsychotics using the conditioned avoidance response model, Society for Neuroscience, November 13-17, 2010, San Diego.

20.       Zhao, CJ, Sun, T, and Li, M: Neuroanatomical mechanisms underlying the inhibitory effect of repeated antipsychotic treatment on repeated phencyclidine-induced hyperlocomotion, Society for Neuroscience, November 13-17, 2010, San Diego.

21.       Li, M and Zhao, CJ: c-Fos identification of neuroanatomical sites associated with haloperidol and clozapine disruption of maternal behavior in the rat, Society of Behavioral Endocrinology, July 18-21, 2010, Toronto, Canada.

22.       Li, M, Sun, T, Zhao, CJ, and Hu, G: Distinct neural mechanisms underlying acute and repeated administration of antipsychotic drugs in rat avoidance conditioning, Society of Biological Psychiatry, May 20-23, 2010, New Orleans.

23.       Li, M, He, W, and Chen, J: Effects of different regimens of repeated amphetamine and phencyclidine treatment on prepulse inhibition in rats, Society for Neuroscience, October 16-21, 2009, Chicago.

24.       Zhao, CJ, and Li, M: The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: A double dissociation between dopamine D2 and 5-HT2A/2C Receptors, Society for Neuroscience, October 16-21, 2009, Chicago.

25.       Li, M, Tao, S, and Hu, G: Repeated antipsychotic treatment progressively potentiates inhibition on phencyclidine-induced hyperlocomotion, but attenuates inhibition on amphetamine-induced hyperlocomotion: Relevance to animal models of antipsychotic drugs, Society for Neuroscience, Nov. 14-18, 2008, Washington, DC.

26.       Li, M, Munro, R, Mead, A, and He, W: Sensitization to amphetamine, but not phencyclidine, enhances avoidance responding to a less salient stimulus but does not impair social interaction and social memory in rats, Society for Neuroscience, Nov. 3-7, 2007, San Diego.

27.       Mead, A, and Li, M: Avoidance-suppressing effect of antipsychotic drugs is enhanced after repeated administration: an interoceptive drug memory mechanism, Society for Neuroscience, Nov. 3-7, 2007, San Diego.

28.       Munro R, He W, and Li M, “Amphetamine sensitization leads to abnormally heightened response to a less salient stimulus but does not impair social interaction and social memory”, Midwestern Psychological Association Conference, May 3 - 5, 2007, Chicago.

29.       Li, M, Mead, A, and Weishahn, Anxiolytic property of atypical antipsychotics: A preclinical investigation, Colorado Springs, Mar. 28-April 1, 2007

30.       Li, M, Fletcher, P, and Kapur, S. Examining the time course of antipsychotic treatment in schizophrenia using conditioned avoidance response model, Program No. 453.17. Washington, DC: Society for Neuroscience, Nov. 12-16, 2005.

31.       Ni X, Li M, Han J, Lu Y, Dixon L, Kapur S, Kennedy JL. Investigation of correlations between gene expression of gap junctions and acquisition and performance scores of conditioned avoidance response in rats. 60th Annual meeting of Society of Biological Psychiatry: Pathogenesis and Prevention of Major Mental Disorders, Atlanta, Georgia, USA, May 19-21, 2005.

32.       Smith A., Li M, and Kapur, S. Understanding the Early-Onset of Antipsychotic Action: An Animal and Computational Model, 10th International Congress on Schizophrenia Research, Savannah, Georgia, USA, April 2-6, 2005.

33.       Li, M, Budin, R, Fleming, AS, and Kapur S. (2004) Effects of chronic typical and atypical antipsychotic drug treatment on maternal behavior in rats, Society of Biological Psychiatry's 59th Annual Scientific Convention, New York, April 28-May 1, 2004.

34.       Smith A. J, Becker S, Li M, et al. (2004) A computational model of dopamine in conditioned avoidance and impulsivity, Society of Biological Psychiatry's 59th Annual Scientific Convention, New York, April 28-May 1, 2004.

35.       Li, M, Fletcher, PJ, and Kapur, S. (2003) Antipsychotics suppress stimulus incentive salience: Implications for their therapeutic actions in schizophrenia, 9th International Congress on Schizophrenia Research, Colorado Springs, March 29-April 2, 2003.

36.       Budin R, Li, M, Davidson, P. Fleming, AS, and Kapur, S (2003) Effects of typical and atypical antipsychotics on maternal behavior in postpartum female rats, 9th International Congress on Schizophrenia Research, Colorado Springs, March 29-April 2, 2003.

37.       Li. M, Davidson, P, Fleming, A, and Kapur, S (2002) Effects of typical and atypical antipsychotic drugs on maternal behavior: implications for behavioral mechanisms of antipsychotics, Orlando, Society for Neuroscience Conference, Nov, 2-7.

38.       Li, M, Smith, M-L, and Fleming, A. (2001) Nucleus accumbens shell mediates the consolidation of maternal experiences, San Diego, Society for Neuroscience Conference, Nov, 9-15.

39.       Li, M, Kapur, S, and Fleming, A (2001). Antipsychotics interfere with maternal and social behaviors in rats: Differential effects of haloperidol and clozapine. 8th International Congress on Schizophrenia Research, Whistler Resort, British Columbia, Canada, April 28-May 2, 2001.

40.       Li, M. and Fleming, A. (1999) Effects of lesions of two different subregions of the nucleus accumbens on maternal experience in postpartum rats. Abstracts of Society for Behavioral Neuroendocrinology, 236, 3rd annual meeting, University of Virgina, Charlottesville, Virginia.


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